PHLDA1


Summary: This gene encodes an evolutionarily conserved proline-histidine rich nuclear protein. The encoded protein may play an important role in the anti-apoptotic effects of insulin-like growth factor-1. [provided by RefSeq, Jul 2008].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
pleckstrin homology like domain family A member 1MIM:605335Ensembl:ENSG00000139289HGNC:HGNC:8933PA3327412q21.2

GO terms in PHLDA1


Term TypeEvidence TypeGO Term IDGO Des.
MFIPIGO:0005515protein binding
CCIDAGO:0005634nucleus
CCIDAGO:0005730nucleolus
CCTASGO:0005829cytosol
CCIEAGO:0031410cytoplasmic vesicle
BPTASGO:0000086G2/M transition of mitotic cell cycle
BPIEAGO:0006915apoptotic process
BPIEAGO:0045210FasL biosynthetic process

Gene expression in normal tissue: PHLDA1

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in PHLDA1


DatabasePathway IDPathway Des.
reactomeR-HSA-1640170Cell Cycle
reactomeR-HSA-453274Mitotic G2-G2/M phases
reactomeR-HSA-69275G2/M Transition
reactomeR-HSA-69278Cell Cycle, Mitotic
reactomeR-HSA-8854521Interaction between PHLDA1 and AURKA

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259012

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in PHLDA1

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