PRLHR
Summary: PRLHR is a 7-transmembrane domain receptor for prolactin-releasing hormone (PRLH; MIM 602663) that is highly expressed in anterior pituitary (Ozawa et al., 2002 [PubMed 11923475]).[supplied by OMIM, Mar 2008].
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
prolactin releasing hormone receptor | MIM:600895 | Ensembl:ENSG00000119973 | HGNC:HGNC:4464 | PA28847 | 10q26.11 |
GO terms in PRLHR
Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
CC | TAS | GO:0005886 | plasma membrane |
CC | TAS | GO:0005887 | integral component of plasma membrane |
BP | TAS | GO:0007186 | G-protein coupled receptor signaling pathway |
BP | IEA | GO:0007218 | neuropeptide signaling pathway |
BP | TAS | GO:0007565 | female pregnancy |
BP | IEA | GO:0042445 | hormone metabolic process |
MF | TAS | GO:0004930 | G-protein coupled receptor activity |
MF | IEA | GO:0004983 | neuropeptide Y receptor activity |
MF | IPI | GO:0005515 | protein binding |
MF | TAS | GO:0008188 | neuropeptide receptor activity |
Gene expression in normal tissue: PRLHR
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in PRLHR
Database | Pathway ID | Pathway Des. |
---|---|---|
kegg | hsa04080 | Neuroactive ligand-receptor interaction - Homo sapiens (human) |
wikipathways | WP455 | GPCRs, Class A Rhodopsin-like |
reactome | R-HSA-162582 | Signal Transduction |
reactome | R-HSA-372790 | Signaling by GPCR |
reactome | R-HSA-373076 | Class A/1 (Rhodopsin-like receptors) |
reactome | R-HSA-375276 | Peptide ligand-binding receptors |
reactome | R-HSA-500792 | GPCR ligand binding |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in PRLHR