SEARCH

HOME / SEARCH / PURG

PURG

Summary: The exact function of this gene is not known, however, its encoded product is highly similar to purine-rich element binding protein A. The latter is a DNA-binding protein which binds preferentially to the single strand of the purine-rich element termed PUR, and has been implicated in the control of both DNA replication and transcription. This gene lies in close proximity to the Werner syndrome gene, but on the opposite strand, on chromosome 8p11. [provided by RefSeq, Apr 2016].

Name	OMIM ID	Ensembl ID	HGNC ID	PHARMGKB ID	Map Location
purine rich element binding protein G	MIM:618041	Ensembl:ENSG00000172733	HGNC:HGNC:17930	PA134879671	8p12

GO terms in PURG

Term Type	Evidence Type	GO Term ID	GO Des.
BP	IEA	GO:0006357	regulation of transcription by RNA polymerase II
CC	IBA	GO:0005634	nucleus
CC	IEA	GO:0005634	nucleus
MF	IBA	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
MF	ISA	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
MF	IBA	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
MF	IEA	GO:0003677	DNA binding
MF	IBA	GO:0003690	double-stranded DNA binding
MF	HDA	GO:0003723	RNA binding
MF	IBA	GO:0032422	purine-rich negative regulatory element binding
MF	IBA	GO:0043565	sequence-specific DNA binding

Gene expression in normal tissue: PURG

Select Project:

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in PURG

Database	Pathway ID	Pathway Des.

Gene-Drug: Aster Plot

Drug ID	Drug Name	Model Num.
iGMDRD309	17AAG	2
iGMDRD353	PD0325901	2

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in PURG

SITE

DATATYPES

CLASSFICATION

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.