PURG
Summary: The exact function of this gene is not known, however, its encoded product is highly similar to purine-rich element binding protein A. The latter is a DNA-binding protein which binds preferentially to the single strand of the purine-rich element termed PUR, and has been implicated in the control of both DNA replication and transcription. This gene lies in close proximity to the Werner syndrome gene, but on the opposite strand, on chromosome 8p11. [provided by RefSeq, Apr 2016].
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
purine rich element binding protein G | MIM:618041 | Ensembl:ENSG00000172733 | HGNC:HGNC:17930 | PA134879671 | 8p12 |
GO terms in PURG
Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
BP | IEA | GO:0006357 | regulation of transcription by RNA polymerase II |
CC | IBA | GO:0005634 | nucleus |
CC | IEA | GO:0005634 | nucleus |
MF | IBA | GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding |
MF | ISA | GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding |
MF | IBA | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding |
MF | IEA | GO:0003677 | DNA binding |
MF | IBA | GO:0003690 | double-stranded DNA binding |
MF | HDA | GO:0003723 | RNA binding |
MF | IBA | GO:0032422 | purine-rich negative regulatory element binding |
MF | IBA | GO:0043565 | sequence-specific DNA binding |
Gene expression in normal tissue: PURG
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in PURG
Database | Pathway ID | Pathway Des. |
---|
Gene in drug-gene network: Network Plot

Gene-drug targets distribution
Gene Structure: PDB
Models in PURG