RAB11FIP3


Summary: Proteins of the large Rab GTPase family (see RAB1A; MIM 179508) have regulatory roles in the formation, targeting, and fusion of intracellular transport vesicles. RAB11FIP3 is one of many proteins that interact with and regulate Rab GTPases (Hales et al., 2001 [PubMed 11495908]).[supplied by OMIM, Mar 2008].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
RAB11 family interacting protein 3MIM:608738Ensembl:ENSG00000090565HGNC:HGNC:17224PA13495089616p13.3

Gene Categories:

CELL SURFACE

GO terms in RAB11FIP3


Term TypeEvidence TypeGO Term IDGO Des.
BPIEAGO:0000910cytokinesis
BPTASGO:0016192vesicle-mediated transport
BPIBAGO:0032456endocytic recycling
BPIDAGO:0032456endocytic recycling
BPIMPGO:0032465regulation of cytokinesis
BPIDAGO:0070164negative regulation of adiponectin secretion
CCIDAGO:0005654nucleoplasm
CCIDAGO:0005768endosome
CCIBAGO:0005813centrosome
CCIDAGO:0005813centrosome
CCIDAGO:0005815microtubule organizing center
CCTASGO:0005829cytosol
CCIBAGO:0030139endocytic vesicle
CCIBAGO:0030496midbody
CCIDAGO:0030496midbody
CCIBAGO:0032154cleavage furrow
CCIDAGO:0032154cleavage furrow
CCIDAGO:0043231intracellular membrane-bounded organelle
CCIDAGO:0045171intercellular bridge
CCIDAGO:0055037recycling endosome
CCIBAGO:0055038recycling endosome membrane
CCIEAGO:0055038recycling endosome membrane
MFIEAGO:0005509calcium ion binding
MFIPIGO:0005515protein binding
MFIBAGO:0017137Rab GTPase binding
MFIPIGO:0017137Rab GTPase binding
MFNASGO:0017137Rab GTPase binding
MFIBAGO:0030306ADP-ribosylation factor binding
MFIPIGO:0030306ADP-ribosylation factor binding
MFIDAGO:0042803protein homodimerization activity
MFIPIGO:0051959dynein light intermediate chain binding

Gene expression in normal tissue: RAB11FIP3

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in RAB11FIP3


DatabasePathway IDPathway Des.
reactomeR-HSA-1852241Organelle biogenesis and maintenance
reactomeR-HSA-5617833Cilium Assembly
reactomeR-HSA-5620916VxPx cargo-targeting to cilium
reactomeR-HSA-5620920Cargo trafficking to the periciliary membrane
pidarf6downstreampathwayArf6 downstream pathway
kegghsa04144Endocytosis - Homo sapiens (human)

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259012

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in RAB11FIP3

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