RANBP17


Summary: The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors.[supplied by OMIM, Jul 2002].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
RAN binding protein 17MIM:606141Ensembl:ENSG00000204764HGNC:HGNC:14428PA342085q35.1

Gene Categories:

TRANSPORTER

GO terms in RANBP17


Term TypeEvidence TypeGO Term IDGO Des.
MFIBAGO:0005049nuclear export signal receptor activity
MFNASGO:0005525GTP binding
BPNASGO:0006606protein import into nucleus
BPIBAGO:0006611protein export from nucleus
BPIEAGO:0051028mRNA transport
CCIBAGO:0005643nuclear pore
CCNASGO:0005643nuclear pore
CCIBAGO:0005737cytoplasm

Gene expression in normal tissue: RANBP17

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in RANBP17


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD420Leucascandrolide A2
iGMDRD387CHIR-990212
iGMDRD433Lexibulin2
iGMDRD126Tipifarnib7
iGMDRD484Pluripotin2
iGMDRD483SCH-5290741
iGMDRD779PRL-3 Inhibitor I1
iGMDRD152179324-69-73
iGMDRD193Fqi13
iGMDRD71Sparfosic acid3
iGMDRD375GW-4058333
iGMDRD466Chaetocin2
iGMDRD280CYTOCHALASIN B6
iGMDRD8024-methylfasudil4
iGMDRD255SB2250025
iGMDRD870BRD636102
iGMDRD294Batimastat2
iGMDRD441TW 371
iGMDRD171Pemetrexed2
iGMDRD782DC-45-A24
iGMDRD398Sepantronium3
iGMDRD562Navitoclax2
iGMDRD506Fedratinib6
iGMDRD887Compound 23 citrate3
iGMDRD74Idarubicin4
iGMDRD188Piperlongumine2
iGMDRD451Serdemetan5
iGMDRD524ISX-95
iGMDRD598QS-112
iGMDRD64Parbendazole2
iGMDRD60Quinoclamine8
iGMDRD405PIK-753
iGMDRD523Cyanoquinoline, 112
iGMDRD314Tanespimycin1
iGMDRD698Neratinib5
iGMDRD351GW843682X2
iGMDRD154NSC237664
iGMDRD123Isoevodiamine1
iGMDRD137Indisulam5
iGMDRD202Curcumin4
iGMDRD121GMX17783
iGMDRD158NSC1415402
iGMDRD271Brefeldin A3
iGMDRD434BMS-5369243
iGMDRD329Merck606
iGMDRD414MST-3122
iGMDRD322FK 8663
iGMDRD300Tozasertib1

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in RANBP17

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