RTN2


Summary: This gene belongs to the family of reticulon encoding genes. Reticulons are necessary for proper generation of tubular endoplasmic reticulum and likely play a role in intracellular vesicular transport. Alternatively spliced transcript variants encoding different isoforms have been identified. Mutations at this locus have been associated with autosomal dominant spastic paraplegia-12. [provided by RefSeq, Apr 2012].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
reticulon 2MIM:603183Ensembl:ENSG00000125744HGNC:HGNC:10468PA3488119q13.32

GO terms in RTN2


Term TypeEvidence TypeGO Term IDGO Des.
CCIDAGO:0005783endoplasmic reticulum
CCIEAGO:0014802terminal cisterna
CCNASGO:0030176integral component of endoplasmic reticulum membrane
CCIEAGO:0030315T-tubule
BPIEAGO:0046324regulation of glucose import
BPIEAGO:0065002intracellular protein transmembrane transport
MFIPIGO:0005515protein binding

Gene expression in normal tissue: RTN2

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in RTN2


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259011

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in RTN2

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