SALL2


Summary: This gene encodes a protein containing multiple zinc finger domains. The encoded protein functions in optical fissure closure during development of the eye in the embryo. Mutations in this gene are associated with ocular coloboma. [provided by RefSeq, Jul 2016].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
spalt like transcription factor 2MIM:602219Ensembl:ENSG00000165821HGNC:HGNC:10526PA3493414q11.2

GO terms in SALL2


Term TypeEvidence TypeGO Term IDGO Des.
CCIBAGO:0005634nucleus
CCIEAGO:0016581NuRD complex
BPIBAGO:0000122negative regulation of transcription by RNA polymerase II
BPIDAGO:0001654eye development
BPIBAGO:0006355regulation of transcription, DNA-templated
BPIBAGO:0007275multicellular organism development
BPIEAGO:0021915neural tube development
BPIMPGO:0045944positive regulation of transcription by RNA polymerase II
MFIDAGO:0000977RNA polymerase II regulatory region sequence-specific DNA binding
MFISAGO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding
MFNASGO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding
MFIDAGO:0001228transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
MFIMPGO:0001228transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
MFIBAGO:0003700DNA-binding transcription factor activity
MFIPIGO:0005515protein binding
MFIBAGO:0043565sequence-specific DNA binding
MFIBAGO:0044212transcription regulatory region DNA binding
MFIEAGO:0046872metal ion binding

Gene expression in normal tissue: SALL2

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in SALL2


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259011
iGMDRD30917AAG2

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in SALL2

​​​​