SASH3
Summary: The protein encoded by this gene contains a Src homology-3 (SH3) domain and a sterile alpha motif (SAM), both of which are found in proteins involved in cell signaling. This protein may function as a signaling adapter protein in lymphocytes.[provided by RefSeq, Sep 2009].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| SAM and SH3 domain containing 3 | MIM:300441 | Ensembl:ENSG00000122122 | HGNC:HGNC:15975 | PA162402388 | Xq26.1 |
GO terms in SASH3
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IBA | GO:0002639 | positive regulation of immunoglobulin production |
| BP | IEA | GO:0002639 | positive regulation of immunoglobulin production |
| BP | IEA | GO:0002726 | positive regulation of T cell cytokine production |
| BP | IBA | GO:0002821 | positive regulation of adaptive immune response |
| BP | IBA | GO:0009966 | regulation of signal transduction |
| BP | IBA | GO:0030890 | positive regulation of B cell proliferation |
| BP | IEA | GO:0030890 | positive regulation of B cell proliferation |
| BP | IEA | GO:0032729 | positive regulation of interferon-gamma production |
| BP | IEA | GO:0032733 | positive regulation of interleukin-10 production |
| BP | IEA | GO:0032743 | positive regulation of interleukin-2 production |
| BP | IEA | GO:0032753 | positive regulation of interleukin-4 production |
| BP | IEA | GO:0032760 | positive regulation of tumor necrosis factor production |
| BP | IEA | GO:0042102 | positive regulation of T cell proliferation |
| BP | IEA | GO:0043372 | positive regulation of CD4-positive, alpha-beta T cell differentiation |
| BP | IEA | GO:0046622 | positive regulation of organ growth |
| BP | IEA | GO:0048873 | homeostasis of number of cells within a tissue |
| CC | IBA | GO:0005634 | nucleus |
| CC | IEA | GO:0005634 | nucleus |
| CC | IBA | GO:0005737 | cytoplasm |
| CC | IEA | GO:0005737 | cytoplasm |
Gene expression in normal tissue: SASH3
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in SASH3
| Database | Pathway ID | Pathway Des. |
|---|
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in SASH3
CLASSFICATION
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