SCRT1
Summary: This gene encodes a C2H2-type zinc finger transcriptional repressor that binds to E-box motifs. The encoded protein may promote neural differention and may be involved in cancers with neuroendocrine features. [provided by RefSeq, Jul 2013].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| scratch family transcriptional repressor 1 | MIM:605858 | Ensembl:ENSG00000261678 | HGNC:HGNC:15950 | PA35015 | 8q24.3 |
GO terms in SCRT1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IDA | GO:0000122 | negative regulation of transcription by RNA polymerase II |
| BP | IEA | GO:0006351 | transcription, DNA-templated |
| BP | IBA | GO:0006355 | regulation of transcription, DNA-templated |
| BP | TAS | GO:0006355 | regulation of transcription, DNA-templated |
| BP | IEA | GO:2001222 | regulation of neuron migration |
| CC | IBA | GO:0005634 | nucleus |
| CC | IDA | GO:0016604 | nuclear body |
| MF | IDA | GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding |
| MF | ISA | GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding |
| MF | IC | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding |
| MF | IDA | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding |
| MF | IBA | GO:0003677 | DNA binding |
| MF | IBA | GO:0003700 | DNA-binding transcription factor activity |
| MF | NAS | GO:0003700 | DNA-binding transcription factor activity |
| MF | IDA | GO:0043565 | sequence-specific DNA binding |
| MF | IEA | GO:0046872 | metal ion binding |
Gene expression in normal tissue: SCRT1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in SCRT1
| Database | Pathway ID | Pathway Des. |
|---|
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in SCRT1
CLASSFICATION
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