GO terms in SH3GL2


Term TypeEvidence TypeGO Term IDGO Des.
BPIEAGO:0002090regulation of receptor internalization
BPTASGO:0007165signal transduction
BPTASGO:0007417central nervous system development
BPIEAGO:0016191synaptic vesicle uncoating
BPTASGO:0019886antigen processing and presentation of exogenous peptide antigen via MHC class II
BPISSGO:0031175neuron projection development
BPTASGO:0042059negative regulation of epidermal growth factor receptor signaling pathway
BPIEAGO:0060988lipid tube assembly
BPTASGO:0061024membrane organization
BPISSGO:0097484dendrite extension
BPIEAGO:0097749membrane tubulation
BPIEAGO:0097753membrane bending
BPIEAGO:0099050vesicle scission
BPIEAGO:1903527positive regulation of membrane tubulation
BPISSGO:1990416cellular response to brain-derived neurotrophic factor stimulus
BPIEAGO:2000369regulation of clathrin-dependent endocytosis
CCTASGO:0000139Golgi membrane
CCISSGO:0005769early endosome
CCTASGO:0005829cytosol
CCTASGO:0005886plasma membrane
CCTASGO:0030669clathrin-coated endocytic vesicle membrane
CCIEAGO:0043025neuronal cell body
CCIEAGO:0048471perinuclear region of cytoplasm
CCIEAGO:0097441basal dendrite
CCIEAGO:0098793presynapse
MFIPIGO:0005515protein binding
MFIEAGO:0008022protein C-terminus binding
MFIEAGO:0008289lipid binding
MFIEAGO:0019901protein kinase binding
MFIPIGO:0042802identical protein binding
MFIEAGO:0042803protein homodimerization activity

Gene expression in normal tissue: SH3GL2

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in SH3GL2


DatabasePathway IDPathway Des.
netpathPathway_EGFR1EGFR1
piderbb1_internalization_pathwayInternalization of ErbB1
pidmet_pathwaySignaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
pidrhoa_pathwayRhoA signaling pathway
kegghsa04144Endocytosis - Homo sapiens (human)
wikipathwaysWP437EGF-EGFR Signaling Pathway
reactomeR-HSA-1266738Developmental Biology
reactomeR-HSA-1266738Developmental Biology
reactomeR-HSA-1280218Adaptive Immune System
reactomeR-HSA-162582Signal Transduction
reactomeR-HSA-162582Signal Transduction
reactomeR-HSA-1643685Disease
reactomeR-HSA-166520Signaling by NTRKs
reactomeR-HSA-166520Signaling by NTRKs
reactomeR-HSA-168256Immune System
reactomeR-HSA-177504Retrograde neurotrophin signalling
reactomeR-HSA-177504Retrograde neurotrophin signalling
reactomeR-HSA-177929Signaling by EGFR
reactomeR-HSA-182971EGFR downregulation
reactomeR-HSA-187037Signaling by NTRK1 (TRKA)
reactomeR-HSA-187037Signaling by NTRK1 (TRKA)
reactomeR-HSA-199991Membrane Trafficking
reactomeR-HSA-199992trans-Golgi Network Vesicle Budding
reactomeR-HSA-2132295MHC class II antigen presentation
reactomeR-HSA-373760L1CAM interactions
reactomeR-HSA-373760L1CAM interactions
reactomeR-HSA-421837Clathrin derived vesicle budding
reactomeR-HSA-422475Axon guidance
reactomeR-HSA-422475Axon guidance
reactomeR-HSA-432720Lysosome Vesicle Biogenesis
reactomeR-HSA-432722Golgi Associated Vesicle Biogenesis
reactomeR-HSA-437239Recycling pathway of L1
reactomeR-HSA-437239Recycling pathway of L1
reactomeR-HSA-5653656Vesicle-mediated transport
reactomeR-HSA-5663205Infectious disease
reactomeR-HSA-6806834Signaling by MET
reactomeR-HSA-6807004Negative regulation of MET activity
reactomeR-HSA-8856825Cargo recognition for clathrin-mediated endocytosis
reactomeR-HSA-8856828Clathrin-mediated endocytosis
reactomeR-HSA-8875360InlB-mediated entry of Listeria monocytogenes into host cell
reactomeR-HSA-8876384Listeria monocytogenes entry into host cells
reactomeR-HSA-9006934Signaling by Receptor Tyrosine Kinases
reactomeR-HSA-9006934Signaling by Receptor Tyrosine Kinases

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259011

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in SH3GL2

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