SLC16A5


Summary: This gene encodes a member of the monocarboxylate transporter family and the major facilitator superfamily. The encoded protein is localized to the cell membrane and acts as a proton-linked transporter of bumetanide. Transport by the encoded protein is inhibited by four loop diuretics, nateglinide, thiazides, probenecid, and glibenclamide. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
solute carrier family 16 member 5MIM:603879Ensembl:ENSG00000170190HGNC:HGNC:10926PA3581717q25.1

GO terms in SLC16A5


Term TypeEvidence TypeGO Term IDGO Des.
MFIBAGO:0005215transporter activity
MFIBAGO:0008028monocarboxylic acid transmembrane transporter activity
MFIEAGO:0015293symporter activity
BPIBAGO:0015718monocarboxylic acid transport
BPIEAGO:0015718monocarboxylic acid transport
BPIEAGO:0055085transmembrane transport
CCIBAGO:0005887integral component of plasma membrane
CCTASGO:0005887integral component of plasma membrane
CCTASGO:0016020membrane
CCIBAGO:0016021integral component of membrane

Gene expression in normal tissue: SLC16A5

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in SLC16A5


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259012

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in SLC16A5

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