SLC25A3
Summary: The protein encoded by this gene catalyzes the transport of phosphate into the mitochondrial matrix, either by proton cotransport or in exchange for hydroxyl ions. The protein contains three related segments arranged in tandem which are related to those found in other characterized members of the mitochondrial carrier family. Both the N-terminal and C-terminal regions of this protein protrude toward the cytosol. Multiple alternatively spliced transcript variants have been isolated. [provided by RefSeq, Jul 2008].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| solute carrier family 25 member 3 | MIM:600370 | Ensembl:ENSG00000075415 | HGNC:HGNC:10989 | PA35865 | 12q23.1 |
GO terms in SLC25A3
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IBA | GO:0005315 | inorganic phosphate transmembrane transporter activity |
| MF | TAS | GO:0015317 | phosphate:proton symporter activity |
| MF | IDA | GO:0044877 | protein-containing complex binding |
| BP | IBA | GO:0035435 | phosphate ion transmembrane transport |
| BP | IEA | GO:1902600 | proton transmembrane transport |
| CC | IDA | GO:0005739 | mitochondrion |
| CC | TAS | GO:0005887 | integral component of plasma membrane |
| CC | HDA | GO:0016020 | membrane |
| CC | IBA | GO:0031305 | integral component of mitochondrial inner membrane |
| CC | IEA | GO:0043209 | myelin sheath |
| CC | HDA | GO:0070062 | extracellular exosome |
Gene expression in normal tissue: SLC25A3
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in SLC25A3
CLASSFICATION
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