SNX33
Summary: The protein encoded by this gene is involved in cytoskeletal reorganization, vesicle trafficking, endocytosis, and mitosis. The encoded protein is essential for the creation of the cleavage furrow during mitosis and for completion of mitosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| sorting nexin 33 | Ensembl:ENSG00000173548 | HGNC:HGNC:28468 | PA162404345 | 15q24.2 |
GO terms in SNX33
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IPI | GO:0005515 | protein binding |
| MF | IEA | GO:0035091 | phosphatidylinositol binding |
| MF | IPI | GO:0042802 | identical protein binding |
| CC | IDA | GO:0005829 | cytosol |
| CC | IDA | GO:0016020 | membrane |
| CC | IDA | GO:0019898 | extrinsic component of membrane |
| CC | IEA | GO:0030659 | cytoplasmic vesicle membrane |
| CC | IDA | GO:0031410 | cytoplasmic vesicle |
| BP | IMP | GO:0000281 | mitotic cytokinesis |
| BP | IEA | GO:0006886 | intracellular protein transport |
| BP | IMP | GO:0006897 | endocytosis |
| BP | IMP | GO:0007032 | endosome organization |
| BP | IMP | GO:0016197 | endosomal transport |
| BP | IDA | GO:0017038 | protein import |
| BP | IMP | GO:0036089 | cleavage furrow formation |
| BP | IMP | GO:0044351 | macropinocytosis |
| BP | IDA | GO:0045806 | negative regulation of endocytosis |
| BP | IDA | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis |
| BP | IDA | GO:0097320 | plasma membrane tubulation |
| BP | IDA | GO:2000009 | negative regulation of protein localization to cell surface |
| BP | IDA | GO:2000010 | positive regulation of protein localization to cell surface |
Gene expression in normal tissue: SNX33
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in SNX33
CLASSFICATION
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