SP8


Summary: The protein encoded by this gene is an SP family transcription factor that in mouse has been shown to be essential for proper limb development. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
Sp8 transcription factorMIM:608306Ensembl:ENSG00000164651HGNC:HGNC:19196PA1348933907p21.1

GO terms in SP8


Term TypeEvidence TypeGO Term IDGO Des.
MFIBAGO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding
MFISAGO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding
MFIEAGO:0003677DNA binding
MFIEAGO:0046872metal ion binding
CCIBAGO:0005634nucleus
BPIEAGO:0006351transcription, DNA-templated
BPIBAGO:0006357regulation of transcription by RNA polymerase II
BPIEAGO:0009953dorsal/ventral pattern formation
BPIEAGO:0009954proximal/distal pattern formation
BPIEAGO:0030326embryonic limb morphogenesis

Gene expression in normal tissue: SP8

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in SP8


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259011

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in SP8

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