SS18L2


Summary: Synovial sarcomas occur most frequently in the extremities around large joints. More than 90% of cases have a recurrent and specific chromosomal translocation, t(X;18)(p11.2;q11.2), in which the 5-prime end of the SS18 gene (MIM 600192) is fused in-frame to the 3-prime end of the SSX1 (MIM 312820), SSX2 (MIM 300192), or SSX4 (MIM 300326) gene. The SS18L2 gene is homologous to SS18.[supplied by OMIM, Jul 2002].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
SS18 like 2MIM:606473Ensembl:ENSG00000008324HGNC:HGNC:15593PA379903p22.1

GO terms in SS18L2


Term TypeEvidence TypeGO Term IDGO Des.
MFIBAGO:0003712transcription coregulator activity
MFIEAGO:0003713transcription coactivator activity
CCIBAGO:0005634nucleus
BPIBAGO:0045893positive regulation of transcription, DNA-templated
BPIBAGO:0045944positive regulation of transcription by RNA polymerase II
BPIBAGO:0050775positive regulation of dendrite morphogenesis
BPIEAGO:1903508positive regulation of nucleic acid-templated transcription

Gene expression in normal tissue: SS18L2

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in SS18L2


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD68Paclitaxel2

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in SS18L2

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