SYNRG
Summary: This gene encodes a protein that interacts with the gamma subunit of AP1 clathrin-adaptor complex. The AP1 complex is located at the trans-Golgi network and associates specific proteins with clathrin-coated vesicles. This encoded protein may act to connect the AP1 complex to other proteins. Alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
synergin gamma | MIM:607291 | Ensembl:ENSG00000275066 | HGNC:HGNC:557 | PA24847 | 17q12 |
GO terms in SYNRG
Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
CC | TAS | GO:0005737 | cytoplasm |
CC | TAS | GO:0005794 | Golgi apparatus |
CC | TAS | GO:0030121 | AP-1 adaptor complex |
BP | TAS | GO:0006886 | intracellular protein transport |
BP | IEA | GO:0006897 | endocytosis |
MF | IPI | GO:0005515 | protein binding |
Gene expression in normal tissue: SYNRG
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in SYNRG
Database | Pathway ID | Pathway Des. |
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution
Gene Structure: PDB
Models in SYNRG