SEARCH

HOME / SEARCH / TAS2R39

TAS2R39

Summary: The protein encoded by this gene is a bitter taste receptor that detects green tea catechins, soy isoflavones, and theaflavins. The encoded protein is gustducin-linked and may activate alpha gustducin. This gene is intronless. [provided by RefSeq, Dec 2015].

Name	OMIM ID	Ensembl ID	HGNC ID	PHARMGKB ID	Map Location
taste 2 receptor member 39		Ensembl:ENSG00000236398	HGNC:HGNC:18886	PA38739	7q34

Gene Categories:

DRUGGABLE GENOME G PROTEIN COUPLED RECEPTOR

GO terms in TAS2R39

Term Type	Evidence Type	GO Term ID	GO Des.
MF	IEA	GO:0004930	G-protein coupled receptor activity
MF	IBA	GO:0033038	bitter taste receptor activity
MF	IDA	GO:0033038	bitter taste receptor activity
BP	IBA	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste
BP	IDA	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste
BP	TAS	GO:0007186	G-protein coupled receptor signaling pathway
CC	TAS	GO:0005886	plasma membrane
CC	IBA	GO:0016021	integral component of membrane
CC	IC	GO:0016021	integral component of membrane

Gene expression in normal tissue: TAS2R39

Select Project:

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in TAS2R39

Database	Pathway ID	Pathway Des.
kegg	hsa04742	Taste transduction - Homo sapiens (human)
reactome	R-HSA-162582	Signal Transduction
reactome	R-HSA-372790	Signaling by GPCR
reactome	R-HSA-388396	GPCR downstream signalling
reactome	R-HSA-418594	G alpha (i) signalling events
reactome	R-HSA-420499	Class C/3 (Metabotropic glutamate/pheromone receptors)
reactome	R-HSA-500792	GPCR ligand binding

Gene-Drug: Aster Plot

Drug ID	Drug Name	Model Num.
iGMDRD309	17AAG	2

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in TAS2R39

SITE

DATATYPES

CLASSFICATION

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.