TAS2R39
Summary: The protein encoded by this gene is a bitter taste receptor that detects green tea catechins, soy isoflavones, and theaflavins. The encoded protein is gustducin-linked and may activate alpha gustducin. This gene is intronless. [provided by RefSeq, Dec 2015].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
GO terms in TAS2R39
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IEA | GO:0004930 | G-protein coupled receptor activity |
| MF | IBA | GO:0033038 | bitter taste receptor activity |
| MF | IDA | GO:0033038 | bitter taste receptor activity |
| BP | IBA | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste |
| BP | IDA | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste |
| BP | TAS | GO:0007186 | G-protein coupled receptor signaling pathway |
Gene expression in normal tissue: TAS2R39
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in TAS2R39
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| kegg | hsa04742 | Taste transduction - Homo sapiens (human) |
| reactome | R-HSA-162582 | Signal Transduction |
| reactome | R-HSA-372790 | Signaling by GPCR |
| reactome | R-HSA-388396 | GPCR downstream signalling |
| reactome | R-HSA-418594 | G alpha (i) signalling events |
| reactome | R-HSA-420499 | Class C/3 (Metabotropic glutamate/pheromone receptors) |
Gene-Drug: Aster Plot
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Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD309 | 17AAG | 2 |
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Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in TAS2R39
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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