TICRR
Summary: Treslin is involved in the initiation of DNA replication (Kumagai et al., 2010 [PubMed 20116089]).[supplied by OMIM, Apr 2010].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| TOPBP1 interacting checkpoint and replication regulator | MIM:613298 | Ensembl:ENSG00000140534 | HGNC:HGNC:28704 | PA142672278 | 15q26.1 |
GO terms in TICRR
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IDA | GO:0003682 | chromatin binding |
| MF | IPI | GO:0005515 | protein binding |
| BP | ISS | GO:0001731 | formation of translation preinitiation complex |
| BP | ISS | GO:0006260 | DNA replication |
| BP | ISS | GO:0006281 | DNA repair |
| BP | ISS | GO:0007093 | mitotic cell cycle checkpoint |
| BP | ISS | GO:0010212 | response to ionizing radiation |
| BP | IMP | GO:0030174 | regulation of DNA-dependent DNA replication initiation |
| BP | ISS | GO:0033314 | mitotic DNA replication checkpoint |
| CC | IDA | GO:0005634 | nucleus |
| CC | IDA | GO:0005654 | nucleoplasm |
Gene expression in normal tissue: TICRR
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in TICRR
| Database | Pathway ID | Pathway Des. |
|---|
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in TICRR
CLASSFICATION
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