YBX3
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| Y-box binding protein 3 | MIM:603437 | Ensembl:ENSG00000060138 | HGNC:HGNC:2428 | PA26929 | 12p13.2 |
GO terms in YBX3
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | ISS | GO:0005634 | nucleus |
| CC | TAS | GO:0005737 | cytoplasm |
| CC | IDA | GO:0005829 | cytosol |
| CC | IEA | GO:0005844 | polysome |
| CC | ISS | GO:0005923 | bicellular tight junction |
| CC | ISS | GO:0048471 | perinuclear region of cytoplasm |
| BP | IEA | GO:0000122 | negative regulation of transcription by RNA polymerase II |
| BP | IEA | GO:0001701 | in utero embryonic development |
| BP | IEA | GO:0006351 | transcription, DNA-templated |
| BP | IEA | GO:0007283 | spermatogenesis |
| BP | IEA | GO:0008584 | male gonad development |
| BP | TAS | GO:0009409 | response to cold |
| BP | IEA | GO:0009566 | fertilization |
| BP | IEA | GO:0046622 | positive regulation of organ growth |
| BP | IEA | GO:0048642 | negative regulation of skeletal muscle tissue development |
| BP | IMP | GO:0060546 | negative regulation of necroptotic process |
| BP | IC | GO:0070935 | 3'-UTR-mediated mRNA stabilization |
| BP | IMP | GO:0071356 | cellular response to tumor necrosis factor |
| BP | IMP | GO:0071474 | cellular hyperosmotic response |
| BP | IMP | GO:1902219 | negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress |
| BP | ISS | GO:2000767 | positive regulation of cytoplasmic translation |
| MF | IEA | GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding |
| MF | ISA | GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding |
| MF | ISM | GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding |
| MF | NAS | GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding |
| MF | IEA | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding |
| MF | TAS | GO:0003690 | double-stranded DNA binding |
| MF | IEA | GO:0003697 | single-stranded DNA binding |
| MF | NAS | GO:0003700 | DNA-binding transcription factor activity |
| MF | TAS | GO:0003714 | transcription corepressor activity |
| MF | HDA | GO:0003723 | RNA binding |
| MF | ISS | GO:0003730 | mRNA 3'-UTR binding |
| MF | IPI | GO:0005515 | protein binding |
| MF | ISS | GO:0017048 | Rho GTPase binding |
Gene expression in normal tissue: YBX3
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in YBX3
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| wikipathways | WP2290 | RalA downstream regulated genes |
| wikipathways | WP2864 | Apoptosis-related network due to altered Notch3 in ovarian cancer |
| kegg | hsa04530 | Tight junction - Homo sapiens (human) |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in YBX3
CLASSFICATION
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