YEATS2


Summary: Summary: The protein encoded by this gene is a scaffolding subunit of the ATAC complex, which is a complex with acetyltransferase activity on histones H3 and H4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2017].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
YEATS domain containing 2MIM:613373Ensembl:ENSG00000163872HGNC:HGNC:25489PA1349226153q27.1

GO terms in YEATS2


Term TypeEvidence TypeGO Term IDGO Des.
MFISMGO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding
MFIPIGO:0005515protein binding
MFIPIGO:0017025TBP-class protein binding
MFIDAGO:0042393histone binding
MFIDAGO:0140030modification-dependent protein binding
CCIDAGO:0005671Ada2/Gcn5/Ada3 transcription activator complex
CCIEAGO:0072686mitotic spindle
BPIDAGO:0000122negative regulation of transcription by RNA polymerase II
BPIDAGO:0043966histone H3 acetylation
BPIDAGO:0045892negative regulation of transcription, DNA-templated

Gene expression in normal tissue: YEATS2

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in YEATS2


DatabasePathway IDPathway Des.
reactomeR-HSA-3214847HATs acetylate histones
reactomeR-HSA-3247509Chromatin modifying enzymes
reactomeR-HSA-4839726Chromatin organization

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259011

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in YEATS2

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