ZCCHC12


Summary: This gene encodes a downstream effector of bone morphogenetic protein (BMP) signalling. This protein contains a zinc finger domain and functions as a transcriptional coactivator. Variation in this gene may be associated with X-linked cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
zinc finger CCHC-type containing 12MIM:300701Ensembl:ENSG00000174460HGNC:HGNC:27273PA134885304Xq24

GO terms in ZCCHC12


Term TypeEvidence TypeGO Term IDGO Des.
MFIEAGO:0003676nucleic acid binding
MFIPIGO:0005515protein binding
MFIEAGO:0008270zinc ion binding
MFIBAGO:0030374nuclear receptor transcription coactivator activity
CCIBAGO:0016607nuclear speck
BPIEAGO:0006351transcription, DNA-templated
BPIBAGO:0030509BMP signaling pathway
BPIEAGO:1903508positive regulation of nucleic acid-templated transcription

Gene expression in normal tissue: ZCCHC12

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in ZCCHC12


DatabasePathway IDPathway Des.
pidbetacatenin_nuc_pathwayRegulation of nuclear beta catenin signaling and target gene transcription

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD353PD03259011

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in ZCCHC12

​​​​