iGMDRD1010

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Standard Name
Drug Status
Drug Type
Standard NameSRC inhibitor (in combination with PI3K/MEK inhibitors)
Drug StatusFamily/Combination
Drug Typeundefined

Drug-model tissue-cancer distribution: Bubble Plot

LUNtissue: LUN cancer: LUNG model num: 0LUNGtissue: LUNG cancer: Adenoid Cystic Carcinoma of the Lung (LUACC) model num: 1

Drug-gene pathway enrichments

1reactome: AMPK inhibits chREBP transcriptional activation activity1reactome: Integration of energy metabolism1reactome: Signal Transduction1reactome: Metabolism1kegg: Tight junction - Homo sapiens (human)1kegg: Adipocytokine signaling pathway - Homo sapiens (human)1reactome: mTOR signalling1reactome: Generic Transcription Pathway1reactome: RNA Polymerase II Transcription1reactome: Gene expression (Transcription)

Drug-gene GO enrichments

3CC: cytosol2BP: cell cycle arrest2MF: protein serine/threonine kinase activity2CC: nucleoplasm1BP: Golgi localization1BP: regulation of protein kinase B signaling1BP: negative regulation of epithelial cell proliferation involved in prostate gland development1BP: negative regulation of lipid biosynthetic process1BP: canonical Wnt signaling pathway1BP: T cell receptor signaling pathway

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
6794 STK11 1
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Gene in drug-gene network: Network Plot

Models in SRC inhibitor (in combination with PI3K/MEK inhibitors)

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
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