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Sym004
iGMDRD1013
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Standard Name
Drug Status
Standard Name
Sym004
Drug Status
Alone
Drug Targets:
EGFR (extracellular domain)
Drug-model tissue-cancer distribution: Bubble Plot
BOWE
tissue: BOWE cancer: BOWEL model num: 0
BOWEL
tissue: BOWEL cancer: Colorectal Cancer model num: 4
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Drug-gene pathway enrichments
2
reactome: Signal Transduction
2
reactome: SHC1 events in ERBB2 signaling
2
reactome: Signaling by ERBB2
2
reactome: Signaling by Receptor Tyrosine Kinases
2
wikipathways: Ebola Virus Pathway on Host
1
netpath: AndrogenReceptor
1
reactome: Signaling by PTK6
1
reactome: Cargo recognition for clathrin-mediated endocytosis
1
reactome: ERBB2 Activates PTK6 Signaling
1
reactome: Gastrin-CREB signalling pathway via PKC and MAPK
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Drug-gene GO enrichments
5
MF: protein tyrosine kinase activity
4
MF: epidermal growth factor-activated receptor activity
3
BP: positive regulation of ERK1 and ERK2 cascade
3
BP: epidermal growth factor receptor signaling pathway
2
MF: epidermal growth factor binding
2
BP: positive regulation of cell proliferation
2
CC: receptor complex
2
MF: transmembrane receptor protein tyrosine kinase activity
2
BP: positive regulation of protein kinase B signaling
2
BP: signal transduction
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Drug-Gene: Aster Plot
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Gene ID
Gene Name
Model Num.
1956
EGFR
4
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4
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1
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Gene in drug-gene network: Network Plot
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Models in Sym004
Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found
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