iGMDRD1024

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Standard Name
CHEMBL
KEGG Drug ID
DRUGBANK ID
Drug Status
Drug Type
Standard NameTrastuzumab in HER2-ampl
CHEMBLCHEMBL1201585
KEGG Drug IDD03257
DRUGBANK IDDB00072
Drug StatusAlone
Drug TypeBiotech



Drug-model tissue-cancer distribution: Bubble Plot

BREAStissue: BREAS cancer: BREAST model num: 0BREASTtissue: BREAST cancer: Breast Carcinoma model num: 1

Drug-gene pathway enrichments

2reactome: Signal Transduction2reactome: Signaling by NTRKs2reactome: Signalling to RAS2reactome: Innate Immune System2reactome: Developmental Biology2reactome: Signaling by ERBB22reactome: Insulin receptor signalling cascade2reactome: IRS-mediated signalling2reactome: Role of LAT2/NTAL/LAB on calcium mobilization2reactome: Immune System

Drug-gene GO enrichments

2MF: Ras guanyl-nucleotide exchange factor activity2MF: guanyl-nucleotide exchange factor activity1BP: heart trabecula morphogenesis1BP: regulation of pro-B cell differentiation1CC: nucleosome1BP: midbrain morphogenesis1BP: eyelid development in camera-type eye1BP: leukocyte migration1BP: regulation of small GTPase mediated signal transduction1BP: positive regulation of small GTPase mediated signal transduction

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
6654 SOS1 1
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Gene in drug-gene network: Network Plot

Models in Trastuzumab in HER2-ampl

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
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