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iGMDRD115

Canonical SMILES: C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)N

InChI: InChI=1S/C13H11N3O4/c14-7-3-1-2-6-10(7)13(20)16(12(6)19)8-4-5-9(17)15-11(8)18/h1-3,8H,4-5,14H2,(H,15,17,18)

InChI Key: UVSMNLNDYGZFPF-UHFFFAOYSA-N

Standard Name	CHEMBL	Pubchem CID	DRUGBANK ID	Drug Status	Drug Type
Pomalidomide	CHEMBL43452	134780	DB08910	Alone	Small Molecule

Drug Class:

Acids, Carbocyclic Angiogenesis Inhibitors Angiogenesis Modulating Agents Antineoplastic Agents Antineoplastic and Immunomodulating Agents Carboxylic Acids Central Nervous System Depressants COX Inhibitors COX-2 Inhibitors Cytochrome P-450 CYP1A2 Substrates Growth Inhibitors Growth Substances Heterocyclic Compounds Heterocyclic Compounds, 1-Ring Heterocyclic Compounds, 2-Ring Imides Immunologic Factors Immunosuppressive Agents Isoindoles Myelosuppressive Agents P-glycoprotein/ABCB1 Substrates Phthalic Acids Phthalimides Piperidines Piperidones Thalidomide Analog

Drug Targets:

CRBN (Q96SW2)TNF (P01375)PTGS2 (P35354)

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot

Gene ID	Gene Name	Model Num.
51185	CRBN	4

Gene in drug-gene network: Network Plot

Models in Pomalidomide

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