iGMDRD13

Canonical SMILES: C(CCl)NC(=O)N(CCCl)N=O

InChI: InChI=1S/C5H9Cl2N3O2/c6-1-3-8-5(11)10(9-12)4-2-7/h1-4H2,(H,8,11)

InChI Key: DLGOEMSEDOSKAD-UHFFFAOYSA-N

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Standard Name
CHEMBL
Pubchem CID
KEGG Drug ID
DRUGBANK ID
Drug Status
Drug targets (TTD)
Drug Type
Standard NameCarmustine
CHEMBLCHEMBL513
Pubchem CID2578
KEGG Drug IDD00254
DRUGBANK IDDB00262
Drug StatusAlone
Drug targets (TTD)DAP000041
Drug TypeSmall Molecule


Drug Targets:

DNAGSR (P00390)RNA

Drug-model tissue-cancer distribution: Bubble Plot

BRAItissue: BRAI cancer: BRAIN model num: 0BRAINtissue: BRAIN cancer: Glioblastoma Multiforme (GBM) model num: 1

Drug-gene pathway enrichments

1reactome: DNA Damage Reversal1reactome: DNA Repair1reactome: MGMT-mediated DNA damage reversal1pharmgkb: Cyclophosphamide Pathway, Pharmacodynamics1pharmgkb: Busulfan Pathway, Pharmacodynamics

Drug-gene GO enrichments

2CC: nucleoplasm2CC: nucleus1CC: membrane1BP: positive regulation of double-strand break repair1MF: DNA binding1MF: methylated-DNA-[protein]-cysteine S-methyltransferase activity1MF: DNA-methyltransferase activity1MF: methyltransferase activity1MF: calcium ion binding1BP: cellular response to ionizing radiation

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
4255 MGMT 1
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Gene in drug-gene network: Network Plot

Models in Carmustine

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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