iGMDRD167

Canonical SMILES: CC1(CC=C(C2=C1C=CC(=C2)C(=O)NC3=CC=C(C=C3)C(=O)O)C4=CC5=CC=CC=C5N=C4)C

InChI: InChI=1S/C29H24N2O3/c1-29(2)14-13-23(21-15-19-5-3-4-6-26(19)30-17-21)24-16-20(9-12-25(24)29)27(32)31-22-10-7-18(8-11-22)28(33)34/h3-13,15-17H,14H2,1-2H3,(H,31,32)(H,33,34)

InChI Key: WGLMBRZXZDAQHP-UHFFFAOYSA-N

Loading, please wait...
Standard Name
Pubchem CID
Drug Status
Drug Type
Standard NameBMS614
Pubchem CID445091
Drug StatusAlone
Drug TypeSmall Molecule

Drug-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 2

Drug-gene pathway enrichments

2reactome: Mitotic G2-G2/M phases2reactome: Mitotic Prometaphase2reactome: M Phase2reactome: Cyclin A/B1/B2 associated events during G2/M transition2reactome: Cell Cycle2reactome: Cell Cycle, Mitotic2reactome: Mitotic Prophase2reactome: G2/M Transition1reactome: Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex1reactome: Gene expression (Transcription)

Drug-gene GO enrichments

4MF: cyclin-dependent protein serine/threonine kinase activity2MF: protein serine/threonine kinase activity2CC: mitotic spindle2BP: microtubule cytoskeleton organization2CC: cytosol2BP: protein phosphorylation2MF: cyclin binding2CC: nucleus1BP: positive regulation of DNA replication1BP: response to ethanol

Drug-Gene: Aster Plot


Loading, please wait...
Gene ID
Gene Name
Model Num.
983 CDK1 1
Showing 1 to 1 of 1 rows

Gene in drug-gene network: Network Plot

Models in BMS614

Loading, please wait...
Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

​​​​

SITE
DATATYPES
CLASSFICATION
Map

Copyright © 2018 Modellab | All Rights Reserved

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.