iGMDRD17

Canonical SMILES: CC1=C(N=CN1)CSCCNC(=NC)NC#N

InChI: InChI=1S/C10H16N6S/c1-8-9(16-7-15-8)5-17-4-3-13-10(12-2)14-6-11/h7H,3-5H2,1-2H3,(H,15,16)(H2,12,13,14)

InChI Key: AQIXAKUUQRKLND-UHFFFAOYSA-N

Standard NameCHEMBLPubchem CIDKEGG Drug IDDRUGBANK IDDrug StatusDrug targets (TTD)Drug Type
CimetidineCHEMBL30 2756D03503DB00501AloneDAP000338Small Molecule

Drug Class:

Acid ReducersAdjuvantsAlimentary Tract and MetabolismAmidinesAndrogen AntagonistsAnti-Ulcer AgentsAntiandrogensAzolesChemically-Induced DisordersCytochrome P-450 CYP1A2 InhibitorsCytochrome P-450 CYP1A2 Inhibitors (weak)Cytochrome P-450 CYP2D6 InhibitorsCytochrome P-450 CYP2D6 Inhibitors (moderate)Cytochrome P-450 CYP2D6 Inhibitors (weak)Cytochrome P-450 CYP3A InhibitorsCytochrome P-450 CYP3A4 InhibitorsCytochrome P-450 CYP3A4 Inhibitors (weak)Cytochrome P-450 CYP3A5 InhibitorsCytochrome P-450 CYP3A5 Inhibitors (moderate)Cytochrome P-450 CYP3A7 InhibitorsCytochrome P-450 CYP3A7 Inhibitors (moderate)Cytochrome P-450 Enzyme InhibitorsDrug-Related Side Effects and Adverse ReactionsDrugs for Acid Related DisordersDrugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord)Enzyme InhibitorsGastrointestinal AgentsGuanidinesHeterocyclic CompoundsHeterocyclic Compounds, 1-RingHistamine AgentsHistamine AntagonistsHistamine H2 AntagonistsImidazolesMetabolic Side Effects of Drugs and SubstancesNeurotransmitter AgentsOAT1 SubstratesOAT3 SubstratesOCT2 SubstratesP-glycoprotein/ABCB1 Substrates

Drug Targets:

HRH2 (P25021)


Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Gene IDGene NameModel Num.
3429IFI271

Gene in drug-gene network: Network Plot

Models in Cimetidine

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