iGMDRD17

Canonical SMILES: CC1=C(N=CN1)CSCCNC(=NC)NC#N

InChI: InChI=1S/C10H16N6S/c1-8-9(16-7-15-8)5-17-4-3-13-10(12-2)14-6-11/h7H,3-5H2,1-2H3,(H,15,16)(H2,12,13,14)

InChI Key: AQIXAKUUQRKLND-UHFFFAOYSA-N

Loading, please wait...
Standard Name
CHEMBL
Pubchem CID
KEGG Drug ID
DRUGBANK ID
Drug Status
Drug targets (TTD)
Drug Type
Standard NameCimetidine
CHEMBLCHEMBL30
Pubchem CID2756
KEGG Drug IDD03503
DRUGBANK IDDB00501
Drug StatusAlone
Drug targets (TTD)DAP000338
Drug TypeSmall Molecule

Drug Class:

Acid ReducersAdjuvantsAlimentary Tract and MetabolismAmidinesAndrogen AntagonistsAnti-Ulcer AgentsAntiandrogensAzolesChemically-Induced DisordersCytochrome P-450 CYP1A2 InhibitorsCytochrome P-450 CYP1A2 Inhibitors (weak)Cytochrome P-450 CYP2D6 InhibitorsCytochrome P-450 CYP2D6 Inhibitors (moderate)Cytochrome P-450 CYP2D6 Inhibitors (weak)Cytochrome P-450 CYP3A InhibitorsCytochrome P-450 CYP3A4 InhibitorsCytochrome P-450 CYP3A4 Inhibitors (weak)Cytochrome P-450 CYP3A5 InhibitorsCytochrome P-450 CYP3A5 Inhibitors (moderate)Cytochrome P-450 CYP3A7 InhibitorsCytochrome P-450 CYP3A7 Inhibitors (moderate)Cytochrome P-450 Enzyme InhibitorsDrug-Related Side Effects and Adverse ReactionsDrugs for Acid Related DisordersDrugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord)Enzyme InhibitorsGastrointestinal AgentsGuanidinesHeterocyclic CompoundsHeterocyclic Compounds, 1-RingHistamine AgentsHistamine AntagonistsHistamine H2 AntagonistsImidazolesMetabolic Side Effects of Drugs and SubstancesNeurotransmitter AgentsOAT1 SubstratesOAT3 SubstratesOCT2 SubstratesP-glycoprotein/ABCB1 Substrates

Drug Targets:

HRH2 (P25021)


Drug-model tissue-cancer distribution: Bubble Plot

BREAStissue: BREAS cancer: BREAST model num: 0BREASTtissue: BREAST cancer: undefined model num: 1

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Loading, please wait...
Gene ID
Gene Name
Model Num.
3429 IFI27 1
Showing 1 to 1 of 1 rows

Gene in drug-gene network: Network Plot

Models in Cimetidine

Loading, please wait...
Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

​​​​

SITE
DATATYPES
CLASSFICATION
Map

Copyright © 2018 Modellab | All Rights Reserved

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.