IFI27
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| interferon alpha inducible protein 27 | MIM:600009 | Ensembl:ENSG00000165949 | HGNC:HGNC:5397 | PA29643 | 14q32.12 |
GO terms in IFI27
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IPI | GO:0001102 | RNA polymerase II activating transcription factor binding |
| MF | ND | GO:0003674 | molecular_function |
| MF | IDA | GO:0005521 | lamin binding |
| BP | IGI | GO:0000122 | negative regulation of transcription by RNA polymerase II |
| BP | IBA | GO:0006919 | activation of cysteine-type endopeptidase activity involved in apoptotic process |
| BP | IDA | GO:0006919 | activation of cysteine-type endopeptidase activity involved in apoptotic process |
| BP | IGI | GO:0046825 | regulation of protein export from nucleus |
| BP | TAS | GO:0060337 | type I interferon signaling pathway |
| BP | IBA | GO:0097190 | apoptotic signaling pathway |
| BP | IDA | GO:0097190 | apoptotic signaling pathway |
| CC | IDA | GO:0005637 | nuclear inner membrane |
| CC | IBA | GO:0005739 | mitochondrion |
| CC | IDA | GO:0005739 | mitochondrion |
| CC | TAS | GO:0005741 | mitochondrial outer membrane |
| CC | IEA | GO:0016021 | integral component of membrane |
Gene expression in normal tissue: IFI27
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in IFI27
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-1280215 | Cytokine Signaling in Immune system |
| reactome | R-HSA-168256 | Immune System |
| reactome | R-HSA-909733 | Interferon alpha/beta signaling |
| reactome | R-HSA-913531 | Interferon Signaling |
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD624 | BRD-K29086754 | 1 |
| iGMDRD262 | KU-55933 | 2 |
| iGMDRD572 | CAY-10594 | 1 |
| iGMDRD283 | Bosutinib | 1 |
| iGMDRD653 | NVP-BSK805 | 1 |
| iGMDRD142 | NSC74859 | 1 |
| iGMDRD883 | CIL55A | 1 |
| iGMDRD668 | GSK 525762A | 1 |
| iGMDRD687 | I-BET151 | 1 |
| iGMDRD124 | Canertinib | 1 |
| iGMDRD117 | Docetaxel | 1 |
| iGMDRD573 | GSK-1904529A | 1 |
| iGMDRD662 | JQ-1 | 1 |
| iGMDRD87 | Epigallocatechin-3-monogallate | 1 |
| iGMDRD946 | ML320 | 1 |
| iGMDRD1039 | X681640 | 1 |
| iGMDRD17 | Cimetidine | 1 |
| iGMDRD94 | Narciclasine | 1 |
| iGMDRD300 | Tozasertib | 1 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in IFI27
CLASSFICATION
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