IFI27

Summary:

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Nameinterferon alpha inducible protein 27
OMIM IDMIM:600009
Ensembl IDEnsembl:ENSG00000165949
HGNC IDHGNC:HGNC:5397
PHARMGKB IDPA29643
Map Location14q32.12

GO terms in IFI27


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IPI GO:0001102 RNA polymerase II activating transcription factor binding
MF ND GO:0003674 molecular_function
MF IDA GO:0005521 lamin binding
BP IGI GO:0000122 negative regulation of transcription by RNA polymerase II
BP IBA GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
BP IDA GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
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Gene expression in normal tissue: IFI27

16 tissues mixtureadiposeadrenalbrainbreastcolonheartkidneyliverlunglymph nodeovaryprostateskeletal muscletestesthyroidwhite blood cells

Gene-model tissue-cancer distribution: Bubble Plot

LUNtissue: LUN cancer: LUNG model num: 0LUNGtissue: LUNG cancer: undefined model num: 8BOWEtissue: BOWE cancer: BOWEL model num: 0BOWELtissue: BOWEL cancer: undefined model num: 3BREAStissue: BREAS cancer: BREAST model num: 0BREASTtissue: BREAST cancer: undefined model num: 3undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 6

Gene-drug pathway distribution

undefined11Mitosis2Chromatin other2Gastric acid secretion1IGFR signaling1Genome integrity1Other, kinases1

Pathways in IFI27


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Database
Pathway ID
Pathway Des.
reactome R-HSA-1280215 Cytokine Signaling in Immune system
reactome R-HSA-168256 Immune System
reactome R-HSA-909733 Interferon alpha/beta signaling
reactome R-HSA-913531 Interferon Signaling
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD624 BRD-K29086754 1
iGMDRD262 KU-55933 2
iGMDRD572 CAY-10594 1
iGMDRD283 Bosutinib 1
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in IFI27

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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