iGMDRD668

Canonical SMILES: CCNC(=O)CC1C2=NN=C(N2C3=C(C=C(C=C3)OC)C(=N1)C4=CC=C(C=C4)Cl)C

InChI: InChI=1S/C22H22ClN5O2/c1-4-24-20(29)12-18-22-27-26-13(2)28(22)19-10-9-16(30-3)11-17(19)21(25-18)14-5-7-15(23)8-6-14/h5-11,18H,4,12H2,1-3H3,(H,24,29)/t18-/m0/s1

InChI Key: AAAQFGUYHFJNHI-SFHVURJKSA-N

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Standard Name
CHEMBL
Pubchem CID
Drug Status
Drug Type
Standard NameGSK 525762A
CHEMBLCHEMBL1232461
Pubchem CID46943400
Drug StatusAlone
Drug TypeSmall Molecule

Drug Targets:

BRD2BRD3BRD4

Drug Pathways:

Chromatin other

Drug-model tissue-cancer distribution: Bubble Plot

LUNtissue: LUN cancer: LUNG model num: 0LUNGtissue: LUNG cancer: undefined model num: 1undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 7

Drug-gene pathway enrichments

3reactome: Cytokine Signaling in Immune system3reactome: Immune System2reactome: Hemostasis2reactome: GPVI-mediated activation cascade2reactome: Interleukin-3, Interleukin-5 and GM-CSF signaling2reactome: Dectin-2 family2reactome: Signaling by Interleukins2reactome: Innate Immune System2reactome: Role of LAT2/NTAL/LAB on calcium mobilization2reactome: FCERI mediated Ca+2 mobilization

Drug-gene GO enrichments

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
9757 KMT2B 1
6850 SYK 1
3429 IFI27 1
Showing 1 to 3 of 3 rows

Gene in drug-gene network: Network Plot

Models in GSK 525762A

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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