iGMDRD653

Canonical SMILES: C1CNCCC1N2C=C(C=N2)C3=NC4=C(C=CC=C4N=C3)C5=CC(=C(C(=C5)F)CN6CCOCC6)F

InChI: InChI=1S/C27H28F2N6O/c28-23-12-18(13-24(29)22(23)17-34-8-10-36-11-9-34)21-2-1-3-25-27(21)33-26(15-31-25)19-14-32-35(16-19)20-4-6-30-7-5-20/h1-3,12-16,20,30H,4-11,17H2

InChI Key: IBPVXAOOVUAOKJ-UHFFFAOYSA-N

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Standard Name
Pubchem CID
Drug Status
Drug Type
Standard NameNVP-BSK805
Pubchem CID46398800
Drug StatusAlone
Drug TypeSmall Molecule

Drug-model tissue-cancer distribution: Bubble Plot

LUNtissue: LUN cancer: LUNG model num: 0LUNGtissue: LUNG cancer: undefined model num: 1LIVEtissue: LIVE cancer: LIVER model num: 0LIVERtissue: LIVER cancer: undefined model num: 1undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 1

Drug-gene pathway enrichments

1reactome: mTORC1-mediated signalling1reactome: mTOR signalling1reactome: Cytokine Signaling in Immune system1reactome: Immune System1reactome: Interferon Signaling1reactome: Interferon alpha/beta signaling1reactome: Signal Transduction1wikipathways: BDNF-TrkB Signaling1kegg: AMPK signaling pathway - Homo sapiens (human)1pid: Signaling mediated by p38-gamma and p38-delta

Drug-gene GO enrichments

2BP: apoptotic signaling pathway2CC: mitochondrion2BP: activation of cysteine-type endopeptidase activity involved in apoptotic process1MF: translation factor activity, RNA binding1MF: RNA polymerase II activating transcription factor binding1MF: ATP binding1MF: calmodulin binding1MF: elongation factor-2 kinase activity1MF: calcium ion binding1MF: molecular_function

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
29904 EEF2K 1
3429 IFI27 1
Showing 1 to 2 of 2 rows

Gene in drug-gene network: Network Plot

Models in NVP-BSK805

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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