iGMDRD283
Canonical SMILES: CN1CCN(CC1)CCCOC2=C(C=C3C(=C2)N=CC(=C3NC4=CC(=C(C=C4Cl)Cl)OC)C#N)OC
InChI: InChI=1S/C26H29Cl2N5O3/c1-32-6-8-33(9-7-32)5-4-10-36-25-13-21-18(11-24(25)35-3)26(17(15-29)16-30-21)31-22-14-23(34-2)20(28)12-19(22)27/h11-14,16H,4-10H2,1-3H3,(H,30,31)
InChI Key: UBPYILGKFZZVDX-UHFFFAOYSA-N
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Standard Name | CHEMBL | Pubchem CID | DRUGBANK ID | Drug Status | Drug Type |
|---|---|---|---|---|---|
Standard NameBosutinib CHEMBLCHEMBL288441 CHEMBL2131134 Pubchem CID5328940 DRUGBANK IDDB06616 Drug StatusAlone Drug TypeSmall Molecule | |||||
Drug Class:
AminesAntineoplastic AgentsAntineoplastic and Immunomodulating AgentsHeterocyclic CompoundsHeterocyclic Compounds, 1-RingHeterocyclic Compounds, 2-RingImmunosuppressive AgentsKinase InhibitorMyelosuppressive AgentsP-glycoprotein/ABCB1 InhibitorsP-glycoprotein/ABCB1 SubstratesProtein Kinase InhibitorsDrug Targets:
BCR (P11274)ABL1 (P00519)LYN (P07948)HCK (P08631)SRC (P12931)CDK2 (P24941)MAP2K1 (Q02750)MAP2K2 (P36507)MAP3K2 (Q9Y2U5)CAMK2G (Q13555)TECDrug Pathways:
Other, kinasesDrug-model tissue-cancer distribution: Bubble Plot
Drug-gene pathway enrichments
Drug-gene GO enrichments
Drug-Gene: Aster Plot
Gene in drug-gene network: Network Plot
Models in Bosutinib
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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