TYRO3
Summary: The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. The encoded protein has also been identified as a cell entry factor for Ebola and Marburg viruses. [provided by RefSeq, May 2010].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:600341 Ensembl IDEnsembl:ENSG00000092445 HGNC IDHGNC:HGNC:12446 PHARMGKB IDPA37097 Map Location15q15.1 | |||||
GO terms in TYRO3
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | ISS | GO:0005634 | nucleus |
| CC | ISS | GO:0005635 | nuclear envelope |
| CC | IBA | GO:0005737 | cytoplasm |
| CC | ISS | GO:0005789 | endoplasmic reticulum membrane |
| CC | IBA | GO:0005887 | integral component of plasma membrane |
| CC | NAS | GO:0005887 | integral component of plasma membrane |
Gene expression in normal tissue: TYRO3
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in TYRO3
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in TYRO3
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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