iGMDRD242

Canonical SMILES: C1C=CC2C1C(NC3=CC=CC=C23)C4=CC5=C(C=C4Br)OCO5

InChI: InChI=1S/C19H16BrNO2/c20-15-9-18-17(22-10-23-18)8-14(15)19-13-6-3-5-11(13)12-4-1-2-7-16(12)21-19/h1-5,7-9,11,13,19,21H,6,10H2

InChI Key: YOLTZIVRJAPVPH-UHFFFAOYSA-N

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Standard Name
Pubchem CID
Drug Status
Drug Type
Standard NameML050
Pubchem CID3136840
Drug StatusAlone
Drug TypeSmall Molecule

Drug Targets:

GPER1

Drug-model tissue-cancer distribution: Bubble Plot

LUNtissue: LUN cancer: LUNG model num: 0LUNGtissue: LUNG cancer: undefined model num: 2PANCREAtissue: PANCREA cancer: PANCREAS model num: 0PANCREAStissue: PANCREAS cancer: undefined model num: 1undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 3

Drug-gene pathway enrichments

1kegg: MicroRNAs in cancer - Homo sapiens (human)1kegg: Pathways in cancer - Homo sapiens (human)1kegg: HTLV-I infection - Homo sapiens (human)1kegg: Glioma - Homo sapiens (human)1kegg: Prostate cancer - Homo sapiens (human)1kegg: Central carbon metabolism in cancer - Homo sapiens (human)1kegg: Melanoma - Homo sapiens (human)1kegg: Human papillomavirus infection - Homo sapiens (human)1kegg: Regulation of actin cytoskeleton - Homo sapiens (human)1kegg: Phospholipase D signaling pathway - Homo sapiens (human)

Drug-gene GO enrichments

3MF: platelet-derived growth factor beta-receptor activity3MF: platelet-derived growth factor binding3BP: positive regulation of ERK1 and ERK2 cascade2BP: positive regulation of smooth muscle cell migration2CC: membrane2BP: negative regulation of apoptotic process2BP: positive regulation of smooth muscle cell proliferation2CC: cytoplasm2BP: positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway2MF: platelet-derived growth factor-activated receptor activity

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
5159 PDGFRB 1
7495 XBP1P1 1
Showing 1 to 2 of 2 rows

Gene in drug-gene network: Network Plot

Models in ML050

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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