iGMDRD274

Canonical SMILES: CN1CCC(C(C1)O)C2=C(C=C(C3=C2OC(=CC3=O)C4=CC=CC=C4Cl)O)O

InChI: InChI=1S/C21H20ClNO5/c1-23-7-6-12(17(27)10-23)19-14(24)8-15(25)20-16(26)9-18(28-21(19)20)11-4-2-3-5-13(11)22/h2-5,8-9,12,17,24-25,27H,6-7,10H2,1H3/t12-,17+/m0/s1

InChI Key: BIIVYFLTOXDAOV-YVEFUNNKSA-N

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Standard Name
CHEMBL
Pubchem CID
DRUGBANK ID
Drug Status
Drug targets (TTD)
Drug Type
Standard NameFlavopiridol
CHEMBLCHEMBL2105698 CHEMBL428690
Pubchem CID5287970
DRUGBANK IDDB03496
Drug StatusAlone
Drug targets (TTD)DCL000422
Drug TypeSmall Molecule


Drug-model tissue-cancer distribution: Bubble Plot

SKItissue: SKI cancer: SKIN model num: 0SKINtissue: SKIN cancer: Melanoma (MEL) model num: 1

Drug-gene pathway enrichments

1pid: Regulation of nuclear beta catenin signaling and target gene transcription1pid: Coregulation of Androgen receptor activity1pid: AP-1 transcription factor network1wikipathways: DNA Damage Response (only ATM dependent)1pid: C-MYB transcription factor network1pid: Validated transcriptional targets of deltaNp63 isoforms1pid: Validated transcriptional targets of AP1 family members Fra1 and Fra21pid: FOXM1 transcription factor network1pid: E2F transcription factor network1wikipathways: Senescence and Autophagy in Cancer

Drug-gene GO enrichments

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
1029 CDKN2A 1
Showing 1 to 1 of 1 rows

Gene in drug-gene network: Network Plot

Models in Flavopiridol

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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