iGMDRD301

Canonical SMILES: CC(=O)N1CCN(CC1)C2=CC=C(C=C2)OCC3COC(O3)(CN4C=CN=C4)C5=C(C=C(C=C5)Cl)Cl

InChI: InChI=1S/C26H28Cl2N4O4/c1-19(33)31-10-12-32(13-11-31)21-3-5-22(6-4-21)34-15-23-16-35-26(36-23,17-30-9-8-29-18-30)24-7-2-20(27)14-25(24)28/h2-9,14,18,23H,10-13,15-17H2,1H3/t23?,26-/m0/s1

InChI Key: XMAYWYJOQHXEEK-NASUQTAISA-N

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Standard Name
Pubchem CID
Drug Status
Drug Type
Standard NameKetoconazole
Pubchem CID5702080
Drug StatusAlone
Drug TypeSmall Molecule

Drug-model tissue-cancer distribution: Bubble Plot

OTHEtissue: OTHE cancer: OTHER model num: 0OTHERtissue: OTHER cancer: Cancer of Unknown Primary (CUP) model num: 1

Drug-gene pathway enrichments

1reactome: Metabolism of proteins1reactome: COPII-mediated vesicle transport1reactome: Membrane Trafficking1reactome: ER to Golgi Anterograde Transport1reactome: Asparagine N-linked glycosylation1reactome: Vesicle-mediated transport1reactome: Transport to the Golgi and subsequent modification1reactome: Post-translational protein modification1reactome: Cargo concentration in the ER1kegg: Colorectal cancer - Homo sapiens (human)

Drug-gene GO enrichments

2BP: positive regulation of cell proliferation2BP: epidermal growth factor receptor signaling pathway2CC: extracellular space1BP: mammary gland alveolus development1BP: epithelial cell proliferation involved in mammary gland duct elongation1BP: mammary gland branching involved in thelarche1BP: dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis1BP: response to glucocorticoid1BP: response to cAMP1CC: Golgi membrane

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
374 AREG 1
Showing 1 to 1 of 1 rows

Gene in drug-gene network: Network Plot

Models in Ketoconazole

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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