iGMDRD315

Canonical SMILES: CC1=CC(=C(N1)C=C2C3=C(C=CC(=C3)Cl)NC2=O)C

InChI: InChI=1S/C15H13ClN2O/c1-8-5-9(2)17-14(8)7-12-11-6-10(16)3-4-13(11)18-15(12)19/h3-7,17H,1-2H3,(H,18,19)/b12-7-

InChI Key: XLBQNZICMYZIQT-GHXNOFRVSA-N

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Standard Name
Pubchem CID
Drug Status
Drug Type
Standard NameSU-5614
Pubchem CID6536810
Drug StatusAlone
Drug TypeSmall Molecule

Drug-model tissue-cancer distribution: Bubble Plot

BLOOtissue: BLOO cancer: BLOOD model num: 0BLOODtissue: BLOOD cancer: Acute Myeloid Leukemia (AML) model num: 2

Drug-gene pathway enrichments

1kegg: Ras signaling pathway - Homo sapiens (human)1kegg: Cytokine-cytokine receptor interaction - Homo sapiens (human)1kegg: MAPK signaling pathway - Homo sapiens (human)1wikipathways: Ras Signaling1wikipathways: Wnt-beta-catenin Signaling Pathway in Leukemia1wikipathways: PI3K-Akt Signaling Pathway1kegg: PI3K-Akt signaling pathway - Homo sapiens (human)1kegg: Hematopoietic cell lineage - Homo sapiens (human)1pharmgkb: Pathway_PA1659594251pharmgkb: Sorafenib Pharmacodynamics

Drug-gene GO enrichments

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
2322 FLT3 2
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Gene in drug-gene network: Network Plot

Models in SU-5614

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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