iGMDRD342

Canonical SMILES: CNC(=O)C1=CC2=C(C=C1)C=C(C=C2)C3(CCN4C3=CN=C4)O

InChI: InChI=1S/C18H17N3O2/c1-19-17(22)14-3-2-13-9-15(5-4-12(13)8-14)18(23)6-7-21-11-20-10-16(18)21/h2-5,8-11,23H,6-7H2,1H3,(H,19,22)/t18-/m0/s1

InChI Key: OZPFIJIOIVJZMN-SFHVURJKSA-N

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Standard Name
CHEMBL
Pubchem CID
DRUGBANK ID
Drug Status
Drug Type
Standard NameOrteronel
CHEMBLCHEMBL1921976
Pubchem CID9796590
DRUGBANK IDDB12066
Drug StatusAlone
Drug TypeSmall Molecule

Drug-model tissue-cancer distribution: Bubble Plot

BREAStissue: BREAS cancer: BREAST model num: 0BREASTtissue: BREAST cancer: Invasive Breast Carcinoma (BRCA) model num: 1

Drug-gene pathway enrichments

1reactome: Metabolism of proteins1reactome: COPII-mediated vesicle transport1reactome: Membrane Trafficking1reactome: ER to Golgi Anterograde Transport1reactome: Asparagine N-linked glycosylation1reactome: Vesicle-mediated transport1reactome: Transport to the Golgi and subsequent modification1reactome: Post-translational protein modification1reactome: Cargo concentration in the ER1kegg: Colorectal cancer - Homo sapiens (human)

Drug-gene GO enrichments

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
374 AREG 1
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Gene in drug-gene network: Network Plot

Models in Orteronel

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
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