iGMDRD45
Canonical SMILES: C1CC(=O)NC(=O)C1N2C(=O)C3=CC=CC=C3C2=O
InChI: InChI=1S/C13H10N2O4/c16-10-6-5-9(11(17)14-10)15-12(18)7-3-1-2-4-8(7)13(15)19/h1-4,9H,5-6H2,(H,14,16,17)
InChI Key: UEJJHQNACJXSKW-UHFFFAOYSA-N
Drug Class:
Acids, CarbocyclicAngiogenesis InhibitorsAngiogenesis Modulating AgentsAnti-Bacterial AgentsAnti-Infective AgentsAntineoplastic AgentsAntineoplastic and Immunomodulating AgentsCarboxylic AcidsCardiotoxic antineoplastic agentsCentral Nervous System DepressantsCytochrome P-450 CYP1A2 SubstratesCytochrome P-450 Enzyme InducersCytochrome P-450 Enzyme InhibitorsGrowth InhibitorsGrowth SubstancesHeterocyclic CompoundsHeterocyclic Compounds, 1-RingHeterocyclic Compounds, 2-RingHypotensive AgentsImidesImmunologic FactorsImmunomodulatory AgentsImmunosuppressive AgentsIsoindolesLeprostatic AgentsMyelosuppressive AgentsNoxaePhthalic AcidsPhthalimidesPiperidinesPiperidonesTeratogensToxic ActionsDrug Targets:
CRBN (Q96SW2)TNF (P01375)NFKB1 (P19838)DNAFGFR2 (P21802)PTGS2 (P35354)Nuclear factor kappa-light-chain-enhancer of activated B cellsORM1 (P02763)Drug Pathways:
Cytokine-cytokine receptor interactionNF-kappa B signaling pathwayHematopoietic cell lineageTNF signaling pathwayDrug-model tissue-cancer distribution: Bubble Plot
Drug-gene pathway enrichments
Drug-gene GO enrichments
Drug-Gene: Aster Plot
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Gene ID | Gene Name | Model Num. |
|---|---|---|
| 6426 | SRSF1 | 1 |
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Gene in drug-gene network: Network Plot
Models in Thalidomide
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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