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iGMDRD45

Canonical SMILES: C1CC(=O)NC(=O)C1N2C(=O)C3=CC=CC=C3C2=O

InChI: InChI=1S/C13H10N2O4/c16-10-6-5-9(11(17)14-10)15-12(18)7-3-1-2-4-8(7)13(15)19/h1-4,9H,5-6H2,(H,14,16,17)

InChI Key: UEJJHQNACJXSKW-UHFFFAOYSA-N

Standard Name	CHEMBL	Pubchem CID	KEGG Drug ID	DRUGBANK ID	Drug Status	Drug targets (TTD)	Drug Type
Thalidomide	CHEMBL468	5426	D00754	DB01041	Alone	DAP000865	Small Molecule

Drug Class:

Acids, Carbocyclic Angiogenesis Inhibitors Angiogenesis Modulating Agents Anti-Bacterial Agents Anti-Infective Agents Antineoplastic Agents Antineoplastic and Immunomodulating Agents Carboxylic Acids Cardiotoxic antineoplastic agents Central Nervous System Depressants Cytochrome P-450 CYP1A2 Substrates Cytochrome P-450 Enzyme Inducers Cytochrome P-450 Enzyme Inhibitors Growth Inhibitors Growth Substances Heterocyclic Compounds Heterocyclic Compounds, 1-Ring Heterocyclic Compounds, 2-Ring Hypotensive Agents Imides Immunologic Factors Immunomodulatory Agents Immunosuppressive Agents Isoindoles Leprostatic Agents Myelosuppressive Agents Noxae Phthalic Acids Phthalimides Piperidines Piperidones Teratogens Toxic Actions

Drug Targets:

CRBN (Q96SW2)TNF (P01375)NFKB1 (P19838)DNA FGFR2 (P21802)PTGS2 (P35354)Nuclear factor kappa-light-chain-enhancer of activated B cells ORM1 (P02763)

Drug Pathways:

Cytokine-cytokine receptor interaction NF-kappa B signaling pathway Hematopoietic cell lineage TNF signaling pathway

Drug Synonyms:

Thalidomide (JAN/USP/INN)Thalomid (TN)Thaled (TN)

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot

Gene ID	Gene Name	Model Num.
6426	SRSF1	1

Gene in drug-gene network: Network Plot

Models in Thalidomide

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Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.