iGMDRD553


Canonical SMILES: C1CN(CC1C(=O)NC2=CC3=C(C=C2)NN=C3C4=CC=NC=C4)CC(=O)N5CCN(CC5)C6=CC=C(C=C6)C7=NC=CC=N7

InChI: InChI=1S/C33H33N9O2/c43-30(42-18-16-41(17-19-42)27-5-2-24(3-6-27)32-35-11-1-12-36-32)22-40-15-10-25(21-40)33(44)37-26-4-7-29-28(20-26)31(39-38-29)23-8-13-34-14-9-23/h1-9,11-14,20,25H,10,15-19,21-22H2,(H,37,44)(H,38,39)/t25-/m1/s1

InChI Key: HDAJDNHIBCDLQF-RUZDIDTESA-N

Loading, please wait...
Standard Name
CHEMBL
Pubchem CID
Drug Status
Drug Type
Standard NameSCH772984
Pubchem CID24866300
Drug StatusAlone
Drug TypeSmall Molecule

Drug-model tissue-cancer distribution: Bubble Plot

PANCREAtissue: PANCREA cancer: PANCREAS model num: 0PANCREAStissue: PANCREAS cancer: Pancreatic Adenocarcinoma (PAAD) model num: 1

Drug-gene pathway enrichments

2reactome: Signal Transduction2reactome: GRB2 events in ERBB2 signaling2reactome: Signaling by ERBB22reactome: p38MAPK events2reactome: Signaling by NTRK1 (TRKA)2reactome: Signalling to ERKs2reactome: Signaling by Receptor Tyrosine Kinases2reactome: Signalling to RAS2reactome: Signaling by NTRKs1reactome: Signaling by RAS mutants

Drug-gene GO enrichments

1CC: cytoplasm1CC: mitochondrion1CC: cytosol1CC: plasma membrane1BP: positive regulation of cellular senescence1BP: epithelial tube branching involved in lung morphogenesis1BP: positive regulation of NF-kappaB transcription factor activity1BP: striated muscle cell differentiation1BP: response to glucocorticoid1BP: response to mineralocorticoid

Drug-Gene: Aster Plot


Loading, please wait...
Gene ID
Gene Name
Model Num.
3845 KRAS 1
Showing 1 to 1 of 1 rows

Gene in drug-gene network: Network Plot

Models in SCH772984

Loading, please wait...
Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

​​​​