iGMDRD570

Canonical SMILES: C1CC(=NO)C2=C1C=C(C=C2)C3=CN(N=C3C4=CC=NC=C4)CCO

InChI: InChI=1S/C19H18N4O2/c24-10-9-23-12-17(19(21-23)13-5-7-20-8-6-13)15-1-3-16-14(11-15)2-4-18(16)22-25/h1,3,5-8,11-12,24-25H,2,4,9-10H2/b22-18-

InChI Key: DEZZLWQELQORIU-PYCFMQQDSA-N

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Standard Name
CHEMBL
Pubchem CID
Drug Status
Drug Type
Standard NameMLS006011051
CHEMBLCHEMBL525191
Pubchem CID25093300
Drug StatusAlone
Drug TypeSmall Molecule

Drug Targets:

BRAF

Drug-model tissue-cancer distribution: Bubble Plot

BOWEtissue: BOWE cancer: BOWEL model num: 0BOWELtissue: BOWEL cancer: Colorectal Cancer model num: 1

Drug-gene pathway enrichments

2reactome: Signaling by Receptor Tyrosine Kinases2reactome: Signal Transduction1reactome: Neurotransmitter receptors and postsynaptic signal transmission1reactome: Transmission across Chemical Synapses1wikipathways: Serotonin Receptor 4-6-7 and NR3C Signaling1wikipathways: Serotonin HTR1 Group and FOS Pathway1wikipathways: Estrogen signaling pathway1reactome: Neuronal System1reactome: Spry regulation of FGF signaling1reactome: Prolonged ERK activation events

Drug-gene GO enrichments

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
673 BRAF 1
Showing 1 to 1 of 1 rows

Gene in drug-gene network: Network Plot

Models in MLS006011051

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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