iGMDRD580

Canonical SMILES: CC(C1=NC=C(S1)C(=O)NC2=NC=C(C(=C2)C(F)(F)F)Cl)NC(=O)C3=C(C(=NC=N3)N)Cl

InChI: InChI=1S/C17H12Cl2F3N7O2S/c1-6(28-15(31)12-11(19)13(23)27-5-26-12)16-25-4-9(32-16)14(30)29-10-2-7(17(20,21)22)8(18)3-24-10/h2-6H,1H3,(H,28,31)(H2,23,26,27)(H,24,29,30)/t6-/m1/s1

InChI Key: VWMJHAFYPMOMGF-ZCFIWIBFSA-N

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Standard Name
Pubchem CID
Drug Status
Drug Type
Standard NameMLN2480
Pubchem CID25161200
Drug StatusAlone
Drug TypeSmall Molecule

Drug Targets:

ARAFBRAFRAF1

Drug-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 2

Drug-gene pathway enrichments

1smpdb: Morphine Action Pathway1smpdb: Vitamin A Deficiency1smpdb: Irinotecan Action Pathway1smpdb: Etoposide Action Pathway1smpdb: Irinotecan Metabolism Pathway1smpdb: Ibuprofen Metabolism Pathway1smpdb: Phenytoin (Antiarrhythmic) Action Pathway1smpdb: Ibuprofen Action Pathway1wikipathways: Estrogen metabolism1wikipathways: Liver steatosis AOP

Drug-gene GO enrichments

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
54658 UGT1A1 1
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Gene in drug-gene network: Network Plot

Models in MLN2480

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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