iGMDRD606

Canonical SMILES: CCN1CCC(CC1)N2C=C(N=N2)CNC3=CC(=C4C(=C3)C(=C(C=N4)C#N)NC5=CC(=C(C=C5)F)Cl)Cl

InChI: InChI=1S/C26H25Cl2FN8/c1-2-36-7-5-20(6-8-36)37-15-19(34-35-37)14-31-18-9-21-25(33-17-3-4-24(29)22(27)10-17)16(12-30)13-32-26(21)23(28)11-18/h3-4,9-11,13,15,20,31H,2,5-8,14H2,1H3,(H,32,33)

InChI Key: PHNZIIMWDVXPGG-UHFFFAOYSA-N

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Standard Name
CHEMBL
Pubchem CID
Drug Status
Drug Type
Standard NameCOT Inhibitor-2
CHEMBLCHEMBL527026
Pubchem CID44143400
Drug StatusAlone
Drug TypeSmall Molecule

Drug Targets:

MAP3K8 (COT)

Drug Pathways:

Other, kinases

Drug-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 2SKItissue: SKI cancer: SKIN model num: 0SKINtissue: SKIN cancer: Cutaneous Melanoma (SKCM) model num: 1

Drug-gene pathway enrichments

1wikipathways: Pathways Affected in Adenoid Cystic Carcinoma1wikipathways: miR-targeted genes in squamous cell - TarBase1wikipathways: miR-targeted genes in muscle cell - TarBase1wikipathways: miR-targeted genes in lymphocytes - TarBase1wikipathways: miR-targeted genes in epithelium - TarBase

Drug-gene GO enrichments

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
6035 RNASE1 1
546 ATRX 1
Showing 1 to 2 of 2 rows

Gene in drug-gene network: Network Plot

Models in COT Inhibitor-2

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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