iGMDRD631

Canonical SMILES: C1=CC(=CC=C1C=CC(=O)NO)C(=O)NNC=C2C=CC(=O)C(=C2O)O

InChI: InChI=1S/C17H15N3O6/c21-13-7-6-12(15(23)16(13)24)9-18-19-17(25)11-4-1-10(2-5-11)3-8-14(22)20-26/h1-9,18,23-24,26H,(H,19,25)(H,20,22)/b8-3+,12-9+

InChI Key: DQNFQTHSDKXSEE-YWSGDMFXSA-N

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Standard Name
Pubchem CID
Drug Status
Drug Type
Standard NamePandacostat
Pubchem CID44543700
Drug StatusAlone
Drug TypeSmall Molecule

Drug-model tissue-cancer distribution: Bubble Plot

OVARtissue: OVAR cancer: OVARY model num: 0OVARYtissue: OVARY cancer: undefined model num: 1BOWEtissue: BOWE cancer: BOWEL model num: 0BOWELtissue: BOWEL cancer: undefined model num: 1

Drug-gene pathway enrichments

1reactome: Costimulation by the CD28 family1reactome: CD28 co-stimulation1reactome: CD28 dependent PI3K/Akt signaling1reactome: VEGFA-VEGFR2 Pathway1reactome: Transcriptional Regulation by TP531reactome: PI3K/AKT Signaling in Cancer1reactome: Immune System1reactome: Signaling by VEGF1reactome: Generic Transcription Pathway1reactome: VEGFR2 mediated vascular permeability

Drug-gene GO enrichments

2BP: actin cytoskeleton reorganization2CC: TORC2 complex2BP: regulation of actin cytoskeleton organization1BP: regulation of inflammatory response1BP: positive regulation of protein kinase B signaling1BP: positive regulation of peptidyl-tyrosine phosphorylation1BP: regulation of protein kinase B signaling1BP: regulation of establishment of cell polarity1CC: cytosol1MF: ribosome binding

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
253260 RICTOR 1
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Gene in drug-gene network: Network Plot

Models in Pandacostat

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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