iGMDRD684

Canonical SMILES: C1=CC(=CC=C1CNC2=NC=NC3=C2C=C(C=C3)F)F

InChI: InChI=1S/C15H11F2N3/c16-11-3-1-10(2-4-11)8-18-15-13-7-12(17)5-6-14(13)19-9-20-15/h1-7,9H,8H2,(H,18,19,20)

InChI Key: AWIVHRPYFSSVOG-UHFFFAOYSA-N

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Standard Name
Pubchem CID
Drug Status
Drug Type
Standard NameSpautin-1
Pubchem CID51037400
Drug StatusAlone
Drug TypeSmall Molecule

Drug-model tissue-cancer distribution: Bubble Plot

undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 2

Drug-gene pathway enrichments

2reactome: Interleukin-12 family signaling2reactome: Interferon gamma signaling2reactome: Interleukin-6 signaling2reactome: Signaling by Interleukins2reactome: Interleukin-3, Interleukin-5 and GM-CSF signaling2reactome: Interleukin-6 family signaling2reactome: Interferon Signaling2reactome: Immune System2reactome: Regulation of IFNG signaling2reactome: Interleukin-12 signaling

Drug-gene GO enrichments

4BP: cytokine-mediated signaling pathway4MF: protein tyrosine kinase activity2MF: histone kinase activity (H3-Y41 specific)2MF: growth hormone receptor binding2BP: histone H3-Y41 phosphorylation2BP: JAK-STAT cascade involved in growth hormone signaling pathway2BP: interleukin-12-mediated signaling pathway2BP: erythrocyte differentiation2BP: tyrosine phosphorylation of STAT protein2CC: nucleoplasm

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
3717 JAK2 1
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Gene in drug-gene network: Network Plot

Models in Spautin-1

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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