iGMDRD773

Canonical SMILES: COC(=O)C1=CC(=CC(=C1)C(=O)N2CCN(CC2)C(=O)C3=CC=C(C=C3)C(=N)N)CN4CCN(CC4)C(=N)N

InChI: InChI=1S/C27H34N8O4/c1-39-26(38)22-15-18(17-32-6-8-35(9-7-32)27(30)31)14-21(16-22)25(37)34-12-10-33(11-13-34)24(36)20-4-2-19(3-5-20)23(28)29/h2-5,14-16H,6-13,17H2,1H3,(H3,28,29)(H3,30,31)

InChI Key: IBVRETRIDAQSEM-UHFFFAOYSA-N

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Standard Name
Pubchem CID
Drug Status
Drug Type
Standard NameCBB1007
Pubchem CID72199300
Drug StatusAlone
Drug TypeSmall Molecule

Drug-model tissue-cancer distribution: Bubble Plot

PANCREAtissue: PANCREA cancer: PANCREAS model num: 0PANCREAStissue: PANCREAS cancer: undefined model num: 1

Drug-gene pathway enrichments

1reactome: Mitotic G2-G2/M phases1reactome: Cyclin A/B1/B2 associated events during G2/M transition1reactome: G2/M Transition1reactome: Cell Cycle, Mitotic1reactome: Cell Cycle1reactome: Polo-like kinase mediated events1kegg: Cellular senescence - Homo sapiens (human)1wikipathways: EMT transition in Colorectal Cancer1wikipathways: Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways1pid: FOXM1 transcription factor network

Drug-gene GO enrichments

3MF: RNA polymerase II transcription factor activity, sequence-specific DNA binding2BP: positive regulation of transcription by RNA polymerase II1BP: regulation of cell cycle1BP: regulation of Ras protein signal transduction1BP: positive regulation of transcription, DNA-templated1BP: regulation of cell cycle arrest1BP: negative regulation of cell aging1CC: nucleoplasm1BP: positive regulation of double-strand break repair1BP: regulation of reactive oxygen species metabolic process

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
2305 FOXM1 1
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Gene in drug-gene network: Network Plot

Models in CBB1007

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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