iGMDRD8

Canonical SMILES: CC(C)(C#N)C1=CC(=CC(=C1)CN2C=NC=N2)C(C)(C)C#N

InChI: InChI=1S/C17H19N5/c1-16(2,9-18)14-5-13(8-22-12-20-11-21-22)6-15(7-14)17(3,4)10-19/h5-7,11-12H,8H2,1-4H3

InChI Key: YBBLVLTVTVSKRW-UHFFFAOYSA-N

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Standard Name
CHEMBL
Pubchem CID
KEGG Drug ID
DRUGBANK ID
Drug Status
Drug targets (TTD)
Drug Type
Standard NameAnastrozole
CHEMBLCHEMBL1399
Pubchem CID2187
KEGG Drug IDD00960
DRUGBANK IDDB01217
Drug StatusAlone
Drug targets (TTD)DAP000627
Drug TypeSmall Molecule


Drug Targets:

CYP19A1 (P11511)


Drug-model tissue-cancer distribution: Bubble Plot

BREAStissue: BREAS cancer: BREAST model num: 0BREASTtissue: BREAST cancer: Invasive Breast Carcinoma (BRCA) model num: 1

Drug-gene pathway enrichments

3reactome: Signal Transduction3reactome: Signaling by Receptor Tyrosine Kinases3reactome: Generic Transcription Pathway3reactome: Gene expression (Transcription)3reactome: RNA Polymerase II Transcription2reactome: Intracellular signaling by second messengers2reactome: Transcriptional regulation by RUNX22reactome: Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors2reactome: TFAP2 (AP-2) family regulates transcription of growth factors and their receptors2netpath: Prolactin

Drug-gene GO enrichments

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
2064 ERBB2 1
2099 ESR1 1
Showing 1 to 2 of 2 rows

Gene in drug-gene network: Network Plot

Models in Anastrozole

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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