iGMDRD805


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Standard Name
Drug Status
Drug Type
Standard NameAdjuvant Chemotherapy
Drug StatusClassification
Drug TypeTherapy

Drug-model tissue-cancer distribution: Bubble Plot

LUNtissue: LUN cancer: LUNG model num: 0LUNGtissue: LUNG cancer: Non-Small Cell Lung Cancer (NSCLC) model num: 2

Drug-gene pathway enrichments

2reactome: PIP3 activates AKT signaling2reactome: Intracellular signaling by second messengers2reactome: Regulation of PTEN gene transcription2reactome: Signal Transduction2reactome: PTEN Regulation2reactome: Metabolism of proteins1reactome: Signaling by Interleukins1reactome: Mitotic G2-G2/M phases1reactome: Protein folding1reactome: SUMOylation of transcription factors

Drug-gene GO enrichments

4MF: RNA polymerase II transcription factor activity, sequence-specific DNA binding3BP: negative regulation of transcription, DNA-templated3BP: positive regulation of gene expression3BP: negative regulation of cell proliferation3BP: positive regulation of transcription by RNA polymerase II2BP: intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator2MF: DNA-binding transcription factor activity2BP: DNA damage response, signal transduction by p53 class mediator2CC: nucleoplasm2MF: DNA binding

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
7157 TP53 2
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Gene in drug-gene network: Network Plot

Models in Adjuvant Chemotherapy

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
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