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AR antagonist
iGMDRD822
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Standard Name
Drug Status
Standard Name
AR antagonist
Drug Status
Alone
Drug-model tissue-cancer distribution: Bubble Plot
PROSTAT
tissue: PROSTAT cancer: PROSTATE model num: 0
PROSTATE
tissue: PROSTATE cancer: Prostate Adenocarcinoma (PRAD) model num: 2
PROSTATE
tissue: PROSTATE cancer: Prostate Cancer model num: 1
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Drug-gene pathway enrichments
1
reactome: RNA Polymerase II Transcription
1
reactome: Gene expression (Transcription)
1
reactome: PTEN Regulation
1
reactome: Post-translational protein modification
1
reactome: Ovarian tumor domain proteases
1
reactome: Regulation of PTEN mRNA translation
1
reactome: Regulation of PTEN localization
1
kegg: FoxO signaling pathway - Homo sapiens (human)
1
kegg: Phosphatidylinositol signaling system - Homo sapiens (human)
1
kegg: Inositol phosphate metabolism - Homo sapiens (human)
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Drug-gene GO enrichments
2
BP: negative regulation of phosphatidylinositol 3-kinase signaling
2
BP: negative regulation of cell proliferation
2
CC: cytosol
2
CC: nucleoplasm
2
BP: negative regulation of protein kinase B signaling
2
BP: phosphatidylinositol dephosphorylation
2
MF: phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity
2
CC: cytoplasm
2
BP: negative regulation of protein phosphorylation
2
BP: protein dephosphorylation
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Drug-Gene: Aster Plot
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Gene ID
Gene Name
Model Num.
5728
PTEN
3
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Gene in drug-gene network: Network Plot
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Models in AR antagonist
Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found
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