iGMDRD822

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Standard Name
Drug Status
Standard NameAR antagonist
Drug StatusAlone

Drug-model tissue-cancer distribution: Bubble Plot

PROSTATtissue: PROSTAT cancer: PROSTATE model num: 0PROSTATEtissue: PROSTATE cancer: Prostate Adenocarcinoma (PRAD) model num: 2PROSTATEtissue: PROSTATE cancer: Prostate Cancer model num: 1

Drug-gene pathway enrichments

1reactome: RNA Polymerase II Transcription1reactome: Gene expression (Transcription)1reactome: PTEN Regulation1reactome: Post-translational protein modification1reactome: Ovarian tumor domain proteases1reactome: Regulation of PTEN mRNA translation1reactome: Regulation of PTEN localization1kegg: FoxO signaling pathway - Homo sapiens (human)1kegg: Phosphatidylinositol signaling system - Homo sapiens (human)1kegg: Inositol phosphate metabolism - Homo sapiens (human)

Drug-gene GO enrichments

2BP: negative regulation of phosphatidylinositol 3-kinase signaling2BP: negative regulation of cell proliferation2CC: cytosol2CC: nucleoplasm2BP: negative regulation of protein kinase B signaling2BP: phosphatidylinositol dephosphorylation2MF: phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity2CC: cytoplasm2BP: negative regulation of protein phosphorylation2BP: protein dephosphorylation

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
5728 PTEN 3
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Gene in drug-gene network: Network Plot

Models in AR antagonist

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
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