iGMDRD919

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Standard Name
Drug Status
Drug Type
Standard NameHormone Therapy
Drug StatusClassification
Drug TypeTherapy

Drug-model tissue-cancer distribution: Bubble Plot

BREAStissue: BREAS cancer: BREAST model num: 0BREASTtissue: BREAST cancer: Breast Carcinoma model num: 5

Drug-gene pathway enrichments

2reactome: Gene expression (Transcription)2reactome: Generic Transcription Pathway2reactome: Transcriptional regulation by RUNX22reactome: RNA Polymerase II Transcription2reactome: Regulation of RUNX2 expression and activity1wikipathways: Leptin signaling pathway1wikipathways: Aryl Hydrocarbon Receptor1wikipathways: Nuclear Receptors1wikipathways: miR-targeted genes in muscle cell - TarBase1wikipathways: Integrated Breast Cancer Pathway

Drug-gene GO enrichments

3MF: estrogen receptor activity3MF: RNA polymerase II transcription factor activity, sequence-specific DNA binding2BP: intracellular estrogen receptor signaling pathway2MF: RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding2BP: cellular response to estradiol stimulus1BP: regulation of intracellular estrogen receptor signaling pathway1BP: response to estradiol1BP: regulation of toll-like receptor signaling pathway1BP: regulation of apoptotic process1BP: negative regulation of I-kappaB kinase/NF-kappaB signaling

Drug-Gene: Aster Plot


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Gene ID
Gene Name
Model Num.
2099 ESR1 5
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Gene in drug-gene network: Network Plot

Models in Hormone Therapy

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
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CLASSFICATION
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